1-(2-Bromobenzoyl)-6,7-(methylenedioxy)isoquinoline
نویسندگان
چکیده
In the title mol-ecule, C(17)H(10)BrNO(3), the mean planes of tricycle and bromo-phenyl fragments form a dihedral angle of 75.5 (1)°. In the crystal, π-π inter-actions [centroid-centroid distances = 3.556 (2) and 3.898 (8) Å] between the isoquinoline systems link mol-ecules into stacks parallel to the a axis. The crystal packing also exibits weak inter-molecular C-H⋯O hydrogen bonds.
منابع مشابه
(6,7-Dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone, a new benzylisoquinoline alkaloid from Beilschmiedia brevipes.
The leaves of Beilschmiedia brevipes provided a new benzylisoquinoline alkaloid: (6,7-dimethoxy-4-methylisoquinolinyl)-(4'-methoxyphenyl)-methanone (1) and O,O-dimethylannocherin A (2), a new natural compound which has been synthesized before. Complete 1H- and 13C-NMR data of both compounds were reported. The structures were established through various spectroscopic methods notably 1D- and 2D-N...
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Very few of the more than sixty naturally-occurring isoquinoline alkaloids have been screened for pharmacological activity, although certain members of this class have known hallucinogenic and cardiovascular activity. Recently the suggestion that biosynthetic catecholamine-derived tetrahydroisoquinolines are involved in the etiology of alcoholism has stimulated research into their activity. Bot...
متن کاملSynthesis and in vitro evaluation of tetrahydroisoquinolines with pendent aromatics as sigma-2 (Ï...2) selective ligands
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2010